The present study aimed to predict job burnout in employed men and women based on work-family conflict mediated by perceived social support and psychological capital. This study is applied in terms of its purpose and descriptive in terms of its method and is of the correlation type. The statistical population of this study consists of all men and women employed in governmental and non-governmental offices and organizations in Tehran in the spring of 2024, of which 237 people were selected through available sampling. The research tools included the Job Burnout Questionnaire by Maslach et al. (2001), Multidimensional Measure of Work–Family Conflict by Carlson et al. (2000), Multidimensional Scale of Perceived Social Support by Zimet et al. (1990), and the Psychological Capital Questionnaire by Luthans et al. (2007). The structural model fit was examined using structural equation modeling and SPSS and AMOS software. The results showed that burnout in employed women and men is predicted based on work-family conflict (P=0.001, β=0.500). Burnout in employed women and men is predicted based on work-family conflict with the mediation of perceived social support (P=0.001, Z=5.33). Burnout in employed women and men is predicted based on work-family conflict with the mediation of psychological capital (P=0.001, Z=5.07).
